p62 links the autophagy pathway and the ubiqutin–proteasome

C-terminal fragment of APP interacts with p62, forms an aggregate p62 app

This review discusses new knowledge in p62 biology with a focus on the role of p62 during cellular stress and aging, and in age-related diseases

p62com เข้าสู่ระบบ These results suggest that p62 may bind with C60 to form aggregates and induce autophagy in autophagosomes  The receptor protein p62 plays a role in the degradation of proteins by the proteasome and lysosome, facilitating the cellular maintenance of proteostasis p62 p62 bodies (PubMed:15911346, PubMed:20168092, PubMed:22017874, PubMed APP P05067, 6, EBI-307104, EBI-77613 XENO, Q13501 · ATG8 P38182, 3, EBI-307104, EBI

20รับ100วอเลท APPPS1 Transgenic Mice Behavioral Studies of p62 KO Animals with Implications of a Modulated Function of the Endocannabinoid System